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The results of the INVICTUS trial for personalized post-stroke rehabilitation

Spoke 02
Spoke 02
2 September 2025
The results of the INVICTUS trial for personalized post-stroke rehabilitation

The trial of INVICTUS, an innovative platform that integrates wearable sensors, artificial intelligence, and cloud technologies to support motor rehabilitation for individuals with limb impairments, is in its final stages. The goal is to validate an ecosystem capable of remotely monitoring, analyzing, and supporting rehabilitation activities, both in clinical settings and in everyday life.

The trial involved a group of 12 elderly volunteers (aged 65–80), thanks to the collaboration with Auser Liguria. These volunteers used the INVICTUS ecosystem in a controlled environment at the Savona Campus (University of Genoa), following personalized motor exercise programs. The workflow involves patients using various devices in combination to perform customized rehabilitation exercises, while data is collected, analyzed, and made available to healthcare professionals for continuous monitoring and potential therapy adjustments.

The initiative was presented in Savona in the presence of Marco Testa (UniGe, project stakeholder), Anna Giacobbe (Auser Savona), and project partners.

INVICTUS is part of Spoke 2 within the RAISE ecosystem and was awarded funding through a cascading grant by Spoke 5.

At the heart of the project is a set of interconnected components:
– Sentry (Swhard Srl), an upper limb tracking system based on inertial sensors (IMUs);
– Pinch (EMAC Srl), a CE-certified device for measuring and rehabilitating fine hand movements;
– WeTAG (SmartTrack), an indoor geolocation system for patient tracking;
– AI module (MareGroup), for the automatic recognition of specific exercises within the patient’s overall daily movement;
– Web app (Nextage), for monitoring completed exercises and analyzing aggregated data;
– All supported by a GDPR-compliant cloud platform, a Windows app for managing patients and exercises, and an augmented reality exergame (XR headset), i.e., a video game designed to guide patients through specific exercises.

The INVICTUS trial marks a key step toward its validation as a scalable tele-rehabilitation solution, initially in Liguria and potentially at the national level. The integration of advanced sensors, XR headsets, artificial intelligence, and geolocation systems enables the collection and analysis of previously unavailable data, paving the way for personalized therapies, continuous progress monitoring, and timely interventions.

If results meet expectations, INVICTUS could be adopted in hospitals, rehabilitation centers, and home settings—helping reduce healthcare costs and improve patients’ quality of life—while positioning Liguria as a leader in digital health.

The trial provides multi-level feedback: from healthcare professionals testing its functionality in the field; from volunteers, through anonymous questionnaires evaluating usability and critical issues; and from stakeholders, who assess its clinical impact.

These insights will guide the project’s next steps: enhancing its intuitiveness, ensuring interoperability with existing healthcare systems, and preparing for future large-scale multicenter studies.

Cover Image
Testing the INVICTUS platform
Author: INVICTUS
Credits: INVICTUS and RAISE

Finaziato dall'Unione Europea Ministero dell'Università e della Ricerca Italia Domani Raise